Alzheimer s Disease ( Ad ) - 2192 Words

Alzheimer’s disease (AD) is a cognitive neurodegerative disorder and one of the major forms of dementia; it represents 60-80% of the dementia patients (Barker et at., 2002). It is estimated by the end of 2015, 53 million people of America would be affected and this would almost double by 2025 and triple by 2050, hence making research momentous for the cure (Hebert et al., 2013). It takes almost 8.5 years between the onset of symptoms of the disease and death (Francis, Palmer, Snape et al., 1998). AD affects the hippocampus and the neocortex region of the brain. These are affected by the deposition of amyloid ÃŽ ² in senile plaques, neurofibrilary tangles and the decline of neuronal synapses. The symptoms of AD includes memory loss resulting in disrupted daily life, confusion with place and time, problem with speaking and writing and many other. Earlier research was done on the inhibition of amyloid ÃŽ ², but a relatively new approach is to find inhibitors for acetlycholinesterases enzyme (AChE). The action of AChE results in the blockage of transmission of acetylcholine (ACh), hence hyperphosphorylating the tau protein which affects the breakage of amyloid precursor protein(APP), which firther results in the increase in amyloid ÃŽ ². The binding of AChE causes decrease in the binding of ACh to muscarinic recptor and nicotinic receptors (Francis, Palmer, Sna pe et al., 1998). A recent study has shown that ACh does not only have cognitive functions, it regulates theShow MoreRelatedAlzheimer s Disease ( Ad )1108 Words   |  5 Pages Alzheimer’s Disease (AD) is a form of dementia that affects 5 million people in the United States alone. One out of every three Seniors die of the disease just in the United States; 80 million suffering world wide making AD the 6th largest cause of death (climax) (Humpel 1; Alzheimer’s Association). AD is the most common dementia; affecting the neuroplasticity of the brain resulting in physical shrinking of the tissues; thus causing neurodegeneration. Diagnosis of the disease is complex, costlyRead MoreAlzheimer s Disease ( Ad ) Essay1112 Words   |  5 Pages Alzheimer disease (AD) is the most common cause of dementia in the elderly, accounting for 65–70% of all cases (Jellinger, Janetzky, Attems, Kienzl, 2008). The other dementias are of the Parkinson s group, the fronto-temporal gr oup and the vascular group. The total worldwide yearly costs for the treatment and care of patients suffering from dementia are estimated to be around 250 billion US dollars. The lifetime risk for AD between the ages of 65 and 100 is 33% for men and 45% for women withRead MoreAlzheimer s Disease ( Ad ) Essay1765 Words   |  8 PagesAlzheimer’s Disease is similar to a literal chipping block of the brain; it is like this conscious genetic machine that (figuratively and) continually deep-fries brain cells and makes them clump up into masses that entangle many cognitive processes that allow an individual to be who they are. It is the slow progression into death where the mental faculties are ravaged and pilfered; the sinews that tie each and every neuron and synapse together. Alzheimer’s disease (AD) is a condition where thereRead MoreAlzheimer s Disease ( Ad )1244 Words   |  5 PagesAlzheimer s disease(AD) wrecks memory and other essential mental capacities. Research has shown that numerous individuals with dementia, particularly those who are sixty-five or older, have brain impairments. All through the numerous periods of Alzheimer s disease, people appear to show any indication, yet harmful changes are occurring in the cerebrum. An unnatural deposit of proteins structure amyloid plaques and tau tangles all through the brain, and once the active neurons quit working, theyRead MoreAlzheimer s Disease ( Ad )1112 Words   |  5 PagesAlzheimer’s disease (AD) is a complex, multifactorial neurodegenerative disease that is currently being managed by symptomatic treatment. The affected areas include the central nervous system (CNS) which is made up of the brain and spinal cord. The brain is essential in managing our thoughts, cognitive abilities, and our ability to interact with the environment. AD patients are known to experience symptoms such as memory loss in the early stages which develop into speaking difficulties to eventuallyRead More Alzheimer s Disease ( Ad )1068 Words   |  5 PagesAlzheimer’s disease (AD) is a neurodegenerative disorder characterized by ÃŽ ²-amyloid plaque formation caused by aggregation of ÃŽ ²-amyloid42 within the brain leading to a progressive decline in cognitive function and memory loss (2). Hyperphosphorylated tau protein is occasionally found in brains of AD patients with advanced pathology however, it is not necessarily an indicator of AD but considered a sign of disease severity (2, 4, Kosik et al, 1986). AD is separated into two subcategories followingRead MoreAlzheimer s Disease ( Ad )1172 Words   |  5 PagesAlzheimer’s disease (AD) is a disorder that is characterized by degeneration of the hippocampal and cortical neurons of the brain – causing memory impairment and a decline in cognitive abilities. The current study by Ghoneim et al.1 focuses on the role of three proteins in the pathogenesis of Alzheimer’s. Brain derived neurotrophic factor (BDNF) signaling is important for development and maintenance of normal neuronal circuits in the brain. Glial fibrillary acidic protein (GFAP) is expressed by astrocytesRead MoreAlzheimer s Disease ( Ad )1361 Words   |  6 PagesAlzheimer’s disease (AD), according to Shan (2013), â€Å"is the most common form of dementia. It is a degenerative, incurable, and terminal disease.† (p. 32). AD is a disease in which the brain essentially deteriorates, is vastly progressive, and complex. Because there is no cure for this disease, scientists and researchers should continue seeking effective prevention measures. Alzheimer’s disease accounts for hundreds of thousands of geriatric deaths each year, and affects not only the patient, butRead MoreAlzheimer s Disease ( Ad ) Essay1588 Words   |  7 Pages This paper explores various elements and issues related to Alzheimer’s disease (AD). Topics briefly detailed include etiology, symptomology, diagnosis, neuroanatomy, neurotransmitter systems involved and treatments that focus on neurotransmitters. Emphasis is placed on such topics as cognitive decline and dementia; neurological change; and changes to neurotransmitters and synapses. Details concerning diagnosis and treatment are brief, but do elaborate somewhat on present studies into addressingRead MoreAlzheimer s Disease ( Ad )1067 Words   |  5 Pageswith Alzheimer’s disease (AD). Alzheimer’s disease (AD) is a brain disease that slowly eradicates recollection, thinking skills and slowly the ability to perform menial tasks. Alzheimer’s disease is classified as the loss of cognitive functioning-thinking, remembering, and reasoning- and behavioral abilities to such an extent that it interferes with a person’s daily life and activities. (****1*) Dementia can vary depending on the types of brain changes such as Lewy body disease, (which are abnormalities

Segu a Novel by Maryse Conde - 1548 Words

In the novel Segu, Maryse Conde beautifully constructs personal and in depth images of African history through the use of four main characters that depict the struggles and importance of family in what is now present day Mali. These four characters and also brothers, by the names of Tiekoro, Siga, Naba, and Malobali are faced with a world changing around their beloved city of Bambara with new customs of the Islamic religion and the developing ideas of European commerce and slave trade. These new expansions in Africa become stepping stones for the Troare brothers to face head on and they have brought both victory and heartache for them and their family. These four characters are centralized throughout this novel because they provide the†¦show more content†¦And Naba, who loses his role model, and grieves on his behalf. As Islam continues to spread and conquer more and more lands, the more families become split as parents send their children to schools to learn how to write an d speak Arabic. When Tiekoro left for Timbuktu the Troare family continued to divide and separate due to continuous forces by foreign expansion and hunger for riches. As a son of a slave woman who had drowned herself, Siga isn’t regarded with nearly as high as prestige as Tiekoro is, despite them only being a couple hours apart in age. After being banished away for not being Muslim, Siga adjusted to his environment with the help of a kind boy and, after being a donkey boy for a while, decides to go into trade. Trade goes completely against the respectable income of a Bambara nobleman, which can be made through cultivating agriculture because the Troare family â€Å"owned plenty of good land planted with millet, cotton, and fonio, worked by hundreds of slaves† (Conde 4). Especially because the Mali Empire had been on fertile land where many different kinds of crops such as ones of sorghum, millet, and fonio could be maintained and the domestication of animals like sheep, goats, and cattle had been strong (Africa 141). Although the way of a Bambara had been agriculture, Siga ventured onto occupy the city of Timbuktu and then Fex so tha tShow MoreRelatedEssay on Segu1143 Words   |  5 PagesEssay Number One The Spread of Islam and the Slave Trade Segu is a garden where cunning grows. Segu is built on treachery. Speak of Segu outside Segu, but do not speak of Segu in Segu (Conde 3). These are the symbolic opening words to the novel Segu by Maryse Conde. The kingdom of Segu in the eighteenth and nineteenth century represents the rise and fall of many kingdoms in the pre-colonial Africa. Therefore, Segu indirectly represents the enduring struggles, triumphs, and defeats ofRead More The Spread of Islam and the Slave Trade Essay1127 Words   |  5 PagesThe Spread of Islam and the Slave Trade â€Å"Segu is a garden where cunning grows. Segu is built on treachery. Speak of Segu outside Segu, but do not speak of Segu in Segu† (Conde 3). These are the symbolic opening words to the novel Segu by Maryse Conde. The kingdom of Segu in the eighteenth and nineteenth century represents the rise and fall of many kingdoms in the pre-colonial Africa. Therefore, Segu indirectly represents the enduring struggles, triumphs, and defeats of people who are of AfricanRead MoreSegu by Maryse Conde Essay971 Words   |  4 PagesSegu by Maryse Conde Using specific illustrations from Maryse Condes novel Segu, this is an essay that discusses how the coming of Islam to Bambar society affected that peoples traditional, political, social and economic practices as well as challenging the Bambaras religious beliefs. Before the arrival of Islam, Segu and its people, the Bambaras, were extremely different world from what they became under Islamic rule. The Bambaras were proud people with a long history in farming, andRead MoreStatus of Women in Things Fall Apart1421 Words   |  6 PagesWhen reading Segu and Things Fall Apart, the role of women is a major part of each novel. Their roles are alike in some ways but at the same time they have some slight differences. In Achebe’s text, women do not seem to be of much importance in their day to day life, but they are crucial to the spiritual wellness of their culture. In Conde’s text though, the women are much more respected by the people in their tribe. The level of reverence for women differs greatly in each novel. In Things FallRead MoreAn Analysis of Segu by Maryse Conde Essay1933 Words   |  8 PagesMadeline Sayre Black Studies 49A- MIESCHER Wednesday 12 pm 3-12-13 In the novel Segu, Maryse Conde beautifully constructs personal and in depth images of African history through the use of four main characters that depict the struggles and importance of family in what is now present day Mali. These four characters and also brothers, by the names of Tiekoro, Siga, Naba, and Malobali are faced with a world changing around their beloved city of Bambara with new customs of the Islamic religionRead MoreSegu Literary Analysis1926 Words   |  8 PagesMarlon Molinare Black Studies 49A Prof. Meischer Wednesday @ 1:00pm March 10 2009 Segu Literary Analysis The historical novel Segu by Maryse Condà © is set in the African country of Segu during a time of great cultural change. The African Slave Trade, the spread of Islam, and personal identity challenges were all tremendous and far-reaching issues facing Africa from the late 1700s to early 1800s. Condà © uses the four brothers of the Traore family, Tiekoro, Malobali, Siga, and Naba, to demonstrateRead MoreConflicts in the Novel Segu Essay1188 Words   |  5 PagesControversies and conflicts are many ways to emphasize key characters and plots in many novels. Authors such as, Maryse Conde use change and the effects of change, to help the reader better understand the underlying themes. In the novel Segu, Conde does just this. The controversy of change in religion creates a fairly large civil conflict amongst the Bambara people. This same civil conflict eventually boils over into the controversy of change in people and trade. The effect of this change would laterRead MoreEssay Conflic ts in the novel Segu1189 Words   |  5 Pages Controversies and conflicts are many ways to emphasize key characters and plots in many novels. Authors such as, Maryse Conde use change and the effects of change, to help the reader better understand the underlying themes. In the novel Segu, Conde does just this. The controversy of change in religion creates a fairly large civil conflict amongst the Bambara people. This same civil conflict eventually boils over into the controversy of change in people and trade. The effect of this change wouldRead MoreLearning About a Different Culture in Maryse Conde’s Segu Essay1233 Words   |  5 PagesMaryse Conde’s novel Segu tells the vivid story of a family hurtled into the chaos of a rapidly changing world. Conde does a phenomenal job of putting readers into the mindset of her many colorful characters allowing readers access to thoughts and motivations behind these characters’ actions. The story is exceptionally intricate and yet the individual stories all feel interconnected back to the Traore family who are the focus point of the novel. Various themes all play a part in the telling of Segu

Characteristics of Orientalism, Prejudice free essay sample

Orientalism does not define the differences in origin, cultural practices, or religion for those who belong to either group. These stereotypical views have been problematic for many Arab and Muslim Americans in the years since the 9/11, and despite the Presidents reassurance, many Arabs and Muslims were detained, questioned at length, and some were kept against their will for long periods of time. Ironically, many of those arrested were American born citizens. Racial profiling has been at the forefront of many political discussions, and it would seem that there is still some conflict where civil rights are concealed. As recently as 2007, a bill known as The Violent Radicalization and Homegrown Terrorism Act (S. 1959 / H. R. 1955) has been passed to investigate terrorism. The Center for Constitutional Rights (2007) has argued however, that the bill is unconstitutional and encourages law enforcement officials to unlawfully detain and accuse members of the American public of politically motivated terrorist intentions. We will write a custom essay sample on Characteristics of Orientalism, Prejudice or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Senator Jon Tester (D-MT) (2007) may have stated an opposing view best when he said that S. 1959 will be â€Å"Intruding on the lives and freedom of average Americans and does not make us any safer† (para. 1). Our collective efforts to promote tolerance, understanding and acceptance of Arab and Muslim citizens must begin by educating our children about world religions. Ignorance promotes prejudice and discrimination, and hate crimes are more likely to occur when people fear for their safety. A program designed to foster tolerance introduces different religions to children in schools. Information on Teaching Tolerance (n. d. ) programs is readily available through the Southern Poverty Law Center, and grant money can be obtained for those schools who wish to implement the programs into their curriculum (http://hubpages. om)†. As an individual I feel that all I can do to help with the hate crimes and prejudice is continue to raise my children the way I have raised them all their lives. They are raised to believe that all people are equal, no matter what the color, race, religion or ethnicity. God made us all and will be the judge in our final days who are we to judge, lest we be judged ourselves.

Education will never be as expensive as ignorance Essay Example For Students

Education will never be as expensive as ignorance Essay What are differences between education and Ignorance? Why do many people agree with a quote Education will never be as expensive as ignorance. Most of the people who graduate from colleges know it is the fact that education costs them a huge amount of money. For instance, people have to pay school fees, buy gas to drive to schools, spend time at schools, and commit to their study. Moreover, some students cant afford colleges because their parents arent able to support them to get degrees, so they must get loans from banks. I guess many readers could wonder why the author states that education would be always cheaper than Ignorance. In my opinion, the quote carries a deep meaning Athena people dont have good education and become useless people for the society, It does not only cost them but also the society. This means ignorance of education can make them make mistakes which may cause serious problems to the society. There are several examples to show what damages could happen when people are uneducated. First, some people can become dangerous criminals because they infringe laws unconsciously, and they are not palpable to distinguish good things and bad things. Second, employers dont want to hire workers who dont have a basic requirement to be hired, which is a high school diploma, because they know those workers cant make profits for their companies and work effectively. Last, people who are lazy to study become a burden for people around since people who work hard do many things such as charities and pay more taxes in order to support uneducated people. To conclude, people should take an advantage of education because It can pay off not only for their personal lives but also for the best of the society.